<p><span style="font-size:14px"><span style="font-family:Arial,Helvetica,sans-serif">p53 is a tumor suppressor gene that is fundamental in cell cycle control and apoptosis. Bivalve Parreysia corrugata is an important component of freshwater ecosystem of Indian sub-continent. In the present study an attempt was made to check whether p53 protein and its homologues that are extracted and isolated from filter feeder mussels; can be used as pollution markers.</span></span></p>