<span style="font-size:14px"><span style="font-family:Arial,Helvetica,sans-serif">Chlorpyrifos (CPF) is a broad spectrum organophosphate insecticide (OP) which is commercially used for more than a decade to control insect pest. It is the second largest selling OP and found to be more toxic to fish than organochlorine compounds. CPF passes via air drift or surface runoff into natural waters, where it is accumulated in different organisms living in water, especially in fish, thus making it vulnerable to several prominent effects. CPF is known to inhibit acetylcholinesterase, cause behavioural, neurological, oxidative, histopathological, endocrine and other effects at low doses. The present study reviews the various effects of CPF in fish.</span></span>