<span style="font-size:14px"><span style="font-family:Arial,Helvetica,sans-serif">Wastewater from cephalosporin antibiotic production with high bio-toxicity is hard to degrade, and could cause great harm to environment and human being. In the present paper, wastewater from cephalosporin production was processed with biochemical treatments as hydrolytic acidification, Up-flow Anaerobic Sludge Bed(UASB), Sequencing Batch Reactor Activated Sludge Process(SBR), biological activated carbon process(BAC). Among them, hydrolytic acidification could efficaciously enhance the biodegradability of wastewater, and greatly increase effects of the subsequent anaerobic-aerobic treatment. The final BAC process could effectively eliminate chemical oxygen demand (COD) and chroma of wastewater treated by aerobic treatment, where COD attained below 100mg/L and chroma was 40. Therefore, wastewater after the previous treatments basically conformed to the discharge standard of &quot; Integrated wastewater discharge standard &quot;(GB8978-1996).</span></span>